Endocrine Abstracts

Introduction: Generalized pustular psoriasis is a rare and the most severe form of psoriasis. It is usually seen in adults. Generalized pustular psoriasis is characterized with sudden eruption of yellowish pustule groups on the shiny erythematous skin, measuring 2 to 3 mm, and cover the all body in a short time. In this report, we presented a patient with Cushing’s syndrome (CS) who had determined pustular psoriasis.Case report: A 35 years old woman...

Introduction: Common reasons of chronically elevated liver enzymes are; fatty liver associated with alcohol abuse or obesity, chronic viral hepatitis, autoimmune hepatitis, chronic bilier disease and hereditary metabolic disorders. Adrenocortical insufficiency can also cause elevated liver enzymes. Until now, there are few cases in the literature with abnormal liver function associated with Addison’s disease. We reported this case to kept mind the Addison’s disease w...

Introduction: Periodic review of hospital deaths is important to know the changing pattern of mortality in our environment. Ankara Ataturk Education and Research Hospital is a tertiary center with 18 in-patient beds in Endocrinology and Metabolism Clinic. Critical patients with endocrine-related diseases are also followed in intensive care unit. In this study, we aimed to evaluate demographic characteristics, hospitalization indications and causes of death in patients who died...

Diabetic ketoacidosis (DKA) seen in 10–70% of patients with type 1 diabetes mellitus (DM1) has a significant risk of mortality. We present a DKA in a patient with DM1 resulted in hypokalemia related ECG abnormalities that the diagnosis needed to be differentiated from acute coronary syndrome. A 18-year-old women without any significant past medical history admitted to hospital with a two day history of fatique, weakness, nausea, vomiting. Patient appeared hipovolemic. Vit...

Introduction: Coexistence of type 1 diabetes mellitus (DM) and autoimmune thyroid diseases was shown in previous studies. Thyroid dysfunctions and thyroid autoantibody positiveness were reported in 23–25 and 27–44% of patients with type 1 DM, respectively. In recent years, thyroid ultrasonography (US) is widely used to diagnose autoimmune thyroid diseases with regard to its ability to define thyroid morphology and echogenity. In this study, we aimed to evaluate thyro...

Introduction: Survival is increased in childhood-onset type 1 diabetes mellitus (DM) and approximately half of patients are diagnosed after the age of 15. Thus, a considerable number of patients with type 1 DM are adults. In this study, we aimed to investigate glycemic control and modalities of treatments in adult type 1 DM patients.Material and methods: Data of type 1 DM patients hospitalized between January 2004 and December 2009 were evaluated retrosp...

Objective: The aim of this study was to determine the change in serum ischemia-modified albumin (IMA) level and oxidative stress markers (total antioxidant status, TAS, total oxidant status, TOS) in patients with metabolic syndrome (metS).Research design and methods: We studied 52 metS patients (56.74±12.75 mean age), and 36 control subjects (54.47±6.52 mean age). The presence of metS was diagnosed according to National Cholesterol Education Pr...

Aim: Acromegaly is an endocrine disorder characterized by sustained elevation of circulating GH and insulin-like growth factor (IGF1). IGF1 is a potent mitogen and has a role in the transformation of normal cells to malignant cells. Micronucleus (MN) frequency is a biomarker of chromosomal damage, genome instability and cancer risk. Our study aimed to evaluate spontaneous MN frequency by using the cytokinesis block MN assay to determine genetic damage in lymphoytes of patients...

Introduction: Premature ovarian failure is cessation of ovarian function before the expected age, which is usually accepted to be 40. Autoimmune diseases are a frequently seen group of disorders causing premature ovarian failure. In this study, we aimed to evaluate the frequency of autoimmune thyroiditis in patients with premature ovarian failure.Material and method: Patients who admitted to our thyroid out patient clinic were included to our study. The ...

Objectives: It has been recently recognized that GH may have a role in hematopoiesis and immune system. However, there are conflicting data regarding the effects of GH deficiency (GHD) and/or GH replacement therapy in GH deficient patients on hematopoiesis and immune system. The aim of the present study was to investigate the peripheral blood cell counts, T- and B-lymphocyte subsets and immunoglobulin levels before and after GH replacement therapy in patients with adult onset ...